I've had chronic pouchitis for 10 yrs now and flagyl seems to be the one that always works .Tried cipro, xifaxan, budesonide, suppositories anucort and canasa. But now I have numbness in feet and toes the docs feel is from flagyl. But everytime I stop the flagyl the pouchitis comes back. They tell me the damage is done and can't be fixed but I hope I can not do any more damage. Any ideas?