I have moved this topic here as I had little response on it under the general forum.

Has anyone encountered the diagnosis of eosinophils in their pouch biopsies? My GI wants me to start entecort for this and I have no crohm's diagnosis in the pouch, just chronic inflammation. I am concerned about this as everything I have read indicates tissue injury to the mucosa and this is a rare situation and I wonder if it will affect my ability to maintain my pouch. It occurs when you have too many eocinophils white blood cells that leave the bloodstream and attack tissue, obviously as they are trying to fight the inflammation they a see as a threat.

here is some info on what may cause it.

Medicines that may cause you to have an increase in eosinophils include:

Amphetamines (appetite suppressants)
Certain laxatives containing psyllium
Certain antibiotics (CIpros??)
Interferon
Tranquilizers

This test may help diagnose:

Acute hypereosinophilic syndrome (a rare but sometimes fatal leukemia-like condition)
An allergic reaction (can also reveal how severe the reaction is)
Early stages of Cushing's disease
Infection by a parasite

What Abnormal Results Mean
A high number of eosinophils (eosinophilia) is often linked to allergic diseases and infections from parasites such as worms. A high eosinophil count may be due to:

Asthma
Autoimmune diseases
Eczema
Hay fever
Leukemia