I have a Jpouch and its been a little over two years , Ive been dealing with chronic pouchitis since having the surgery . My question is I was doing pretty good lately ( Im on a round of cipro and taking VSL3 ) but for the most part doing OK . I got a cold and was sick for about a week , ever since then my pouchitis has gotten so bad and i cant seam to get it under control , could my body get immune to the cipro were it just doesnt work anymore . Its been about two weeks since ive had my cold , and i feel horrible . I just constantly go to the bathroom .Any help would be greatly appreciated . Thanks