Even if it's pouchitis, sometimes you just need a different antibiotic. For example, Flagyl didn't work for me, but Cipro did the trick.

Thanks Scott, is it normal not to be able to go during the day then only at night....I find that a bit mad in my head its like when I'm standing up my pouch is blocked and then lying down it isn't or is that a stupid theory. I've never had pouchitis

Cora,
I don't have this exact problem but I do feel much better during the day than I do in the evening. I think it is because by morning time my pouch is completely empty. It is only later in the day when the breakfast, and lunch start making their way out. And of course during the night is usually when supper makes it's way out.
It might just be a timing issue for you.
CJ

I think it is reasonable to try other antibiotics, but since you failed one, I think you should scoped first to confirm pouchitis. You may be on to something when you suggest a mechanical blockage. Some people develop an over stretched pouch, where it can twist or collapse on itself when you try to empty. This sort of defect may not be visible on scope and you need a motility exam, like a defegram, to see it. It is also possible that you have an anal or pouch inlet stricture, although I would not expect you to be able to pass solids while you were asleep (unless your sphincters relaxed enough to allow some to slip by.

Definitely, since you have gone more than a year without this problem, it should be investigated.

Jan