Has anyone experienced moderate-to-severe complications (mainly diarrhea) from the anti-biotic Augmentin affecting your Jpouch? I was diagnosed with an infection in my left, big toe several weeks ago. The doctor prescribed a week's dose of Bactrim but that didn't take care of it completely. Therefore, I was prescribed Augmentin but could not even complete half the cycle before I told my doc about the issues it was causing. I had severe diarrhea for the past 5 days. I even was seen in my local ER for dehydration over the weekend. Believe me, I was attempting to stay hydrated but was losing more than I could put in. They seemed to think the Augmentin affected the bacteria in my GI tract and affected my pouch. Has anyone experienced something similar to this?