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I have chronic sinusitis as well as a j-pouch. I am trying once a day 24 hour Claritin D. I find it works for about 5 hours, and then has no effectiveness. Do you think this is a resultof having no colon, i.e., the medicine is not fully absorbed or passes before all of the drug can be released? If so any suggestions of what to take? I am miserable! But not as miserable as I was with colitis so I'm not really complaining Smiler

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