I would call your doc for a prescription especially knowing you’re about to go on a cruise! I’ve never had pouch symptoms as a result of My menstrual cycle. I’ve had pouchitis, and I’ve had bad periods, and while they share the commonality of “cramping” it’s a different cramping. You know your body, if this feels different than symptoms from a period, I would get a prescription ASAP so it doesn’t ruin your trip. My doc Doesn’t require a scope to write a once in a blue moon prescription for a pouch flareup. Give them a call, it may be a quick appt or they may just send the script!!

I have always had irritation of the pouch/anal area with my cycle.  Now that I don't have the periods anymore, I still get cycles, meaning there will be a PMS-like time and there may be lower back ache, digestive disturbance, and soreness in the anal area and if they go on too long, there can also be increased inflammation in the pouch which leads to night time leakage.  When I have PMS-symptoms, I take "Peacekeeper" from "Herbalogic."  It clears those symptoms up, plus decreases irritability & sleep disturbance that also can accompany the cycle. If I have night leakage, I get more rest and take more visbiome probiotic and it goes away in a couple days.  I can always feel the inflammation because my pants fit tighter around the waist, and that tightness is always there before the leakage, though the inflammation doesn't always lead to leakage.