Hi..I was on entyvio 2 yrs. Every 4 weeks treatments. After 2 yrs..quit working. (J pouch 34 yrs). Suffered with pouch ulcers, blockages, pouchitis, complete raw rectum) etc..Dr now wants to start stelara this Thursday! Went to surgeon for 2nd opinion to remove j pouch & ho perm ileostomy & he agreed but said he would support my decision to go the stelara route. However, he did feel it wouldn't work cause pouch is in an ischemic state also. So I am trying stelara for. Scared but going to try. I wish you the best also!