Since gallbladder disease is a major risk after a colectomy, GLP-1 isn't advisable, as it carries a warning of risk of gallbladder disease and pancreatitis and Ileus (blockage). Blockages and pancreatitis are also a big risk after colectomy. These three things are already known to be far higher risk for j pouchers/ostomates, then, we add in the risks for these same 3 issues that GLP-1 has- and your risks go up exponentially. so you have the J-pouch and the GLP-1 exerting the same risks and it's not a great combo.
I don't know about you, but I can't afford to lose any more of my digestive system, including the risk to my pouch if any of the above occur. I did a ton of research ( I also happen to be a medical research Md.) and was blown away by how risky any of the 'tides would be for a j-poucher. Also, for the record, diabetes and other insulin issues are extremely common after colectomy or can worsen existing issues.