Does anybody use Predisone for pouchitis?? I have had chronic pouchitis since day one of takedown. Jan 1993, and have been on cipro& flagl pretty much since then. I've tried VSL, & Align with no help. 3 mths ago my DR switched Xifaxan or the cipfo and I had a little relief but it;s roaring back again. You all know but I'm just soooo sick & tired of being sick & tired!! Anyway how about Predisone?? I know all about the side effects I fought UC for 10 years before surgury but Damn the stuff is a sledgehammer for inflammation. Any thoughts? Thanks Badguts

Has anyone mentioned Remicade to you? I have had the exact same treatment regimen that you outlined above since 1995. It still works. I rotate cipro/flagyl with xifaxin. I was told if it does not continue to work, Remicade is the next line of treatment. This from 2 different pouch experts. However, it keeps working for me. Like you I tried all the other stuff and it failed.

Mine didn't start after takedown, but last spring. Rotating antibiotics (rifaxin & Levaquin) is helping, but not enough, so we have added a moderate dose of Entocort to the regimin, which helped me last fall, but when I go off (still rotating the ABs) I don't get enough releif. Entocort is a "designer sterioid" and supposedly it is time-released or something so it does not begin to work and be absorbed until it gets to the end of the small intestine (which is where the pouch/inflamation is). It works awesome for me, but I don't know if I can stay on it "forever". Doc/nurse says let's try it "for now" and then we'll deal with "forever" later. It is expensive, but my insurance covers it, thankfully ('cause there is a whole lot of other stuff I need, including my newest docs, that they don't! Grr!)

Hi,My boyfriend has been struggling with inflammation since his surgery in March 2010 and the only thing that would help some was prednisone which he has been on and off for over a year.
Although it does slow down his bm's it is just too risky to continue according to his Dr's.
He will be starting Remicade infusions Feb. 6th and I was hoping someone on this forum has had good results with the Remicade.
Thanks for any info!

On Thursday 2-2 my doc put me on 20mg predisone aday and proctofoam 2 a day. 4 days in and the swelling is down but not out. I go see him in 4 weeks to see what we have got done. I've been on predisone before ( have'nt we all?) I hope I can get off soon but.... I have to have some relief from the chronic pouchitis.

I had remicade almost 2 years ago. I only did 2 infusions because I had a very bad reation to it but it did save my pouch and since then the only thing I take is canassa every night. Just had a scope and it is still lookin good.